Yan Cui
Yan Cui, PhD
Associate Professor, UTHSC
Director of Bioinformatics Core

Phone:  (901) 448-3240
Email:  ycui2@utmem.edu

Additional Contact:
The University of Tennessee Health Science Center
Department of Molecular Sciences
101G Molecular Sciences Building
Memphis, TN 38163

Cui Lab Website

Elucidating causal pathways bridging genotype and phenotype is one of the fundamental challenges for genetic and genomic research. Gene variants that control phenotypes are typically discovered by combined linkage analysis and molecular validation. However, these genotype-phenotype associations do not expose the underlying causal pathways through which gene variants operate on phenotypes. We are exploring genomic and computational approaches to uncover the causal pathways through which genetic loci influence phenotypes and predict the effects of genetic and transcriptional variations/interventions on gene expression and physiological/behavioral phenotypes of individuals with different genetic backgrounds. We believe research towards this direction will ultimately lead to the development of the computational methods that enable personalized predictive genetics and medicine.


Project funded by funded by NIH Grant HD052472. Please view our funding & data sharing policy
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